![Revolution flawless affinity](https://cdn1.cdnme.se/5447227/9-3/22_64e61dfde087c31b3e70ff43.png)
![infuse plex infuse plex](https://cdn.redmondpie.com/wp-content/uploads/2017/01/infuse-5.2-changelog-410x1024.jpg)
Most find that SMB is a very workable connection. Collectively, our findings demonstrate the biological and physiological presence of this sEV-dependent CSR axis in adult brains. If you have been running plex in the past that may be what you want to do, otherwise Infuse is designed originally to be a stand alone app and you can use it without having to install, set up, and maintain an additional application running in the background on your NAS. The proposed CSR axis was supported by 1) differential neurogenesis outcomes in the OB when animals treated with intracerebroventricular (ICV) infusion of sEVs collected from the CP of normal or manganese (Mn)-poisoned mice, 2) progressively diminished SVZ adult neurogenesis in mice following CP-targeted knockdown of SMPD3 to suppress CP sEV secretion, and 3) compromised olfactory performance in these CP-SMPD3-knockdown mice. We discovered the presence of a CP-SVZ regulatory (CSR) axis in which the CP, by secreting small extracellular vesicles (sEVs), regulated adult neurogenesis in the SVZ and maintained olfaction.
![infuse plex infuse plex](https://s3-storage.textopus.nl/wp-content/uploads/2018/04/19150733/infuse-plex-koppelen.png)
The choroid plexus (CP) in brain ventricles secrete cerebrospinal fluid (CSF) that bathes the adjacent subventricular zone (SVZ) the latter is the largest neurogenic region in adult brain harboring neural stem/progenitor cells (NSPCs) and supplies newborn neurons to the olfactory bulb (OB) for normal olfaction.
![Revolution flawless affinity](https://cdn1.cdnme.se/5447227/9-3/22_64e61dfde087c31b3e70ff43.png)